Author's response to reviews Title:Effect of Electroacupuncture Stimulation at Zusanli Acupoint (ST36) on Gastric Motility: Possible through PKC and MAPK Signal Transduction Pathways Authors:

نویسندگان

  • Qi Yang
  • Yan-Dong Xie
  • Bo Huang
  • Chao Zhang
  • Hui-Yan Li
  • Rong Zhang
  • Ming Qin
  • Yu-Xin Huang
  • Jing-Jie Wang
  • M Nascimento
  • Jiande Chen
چکیده

Author's response to reviews: see over Dear editor, We are pleased to answer the questions of the reviewers' and the manuscript (MS: 1935814324106763) has also been extensively revised according to the comments and the journal style. This paper was proofread by a native English professional with science background. We are appreciating for each editor's hard work on our manuscript. The manuscript is original in scope and has not been considered elsewhere. The introductory material consists of sentence that carries the reader into the topic There is a logical arrangement of later parts and there is a large body of research in the reference notes. To my understanding, the general subject of the review is quite interesting. However, I think that the manuscript has points that should be observed. 1. Analysis of western blot showed up regulation of CaD and CaP protein expression, but it is necessary to show the results of the densitometric analysis of these bands in which the protein levels were normalized for #-actin. Answer: We showed the results of the densitometric analysis of these bands in which the protein levels were normalized for β-actin in Fig 1. 2. In some occasions add transitions so that it flows from one section to the next. Answer: This paper was proofread by a native English professional with science background and rewrite in some sections.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of electroacupuncture stimulation at Zusanli acupoint (ST36) on gastric motility: possible through PKC and MAPK signal transduction pathways

BACKGROUND Electroacupuncture (EA) stimulation has been shown to have a great therapeutic potential for treating gastrointestinal motility disorders. However, no evidence has clarified the mechanisms contributing to the effects of EA stimulation at the Zusanli acupoint (ST.36). This study was designed to investigate the regulative effect of EA stimulation at the ST.36 on gastric motility and to...

متن کامل

Electroacupuncture at PC6 or ST36 Influences the Effect of Tacrine on the Motility of Esophagus

Aim. To investigate the mechanisms of gastrointestinal side effects of tacrine, and find treatment methods with electroacupuncture (EA). Methods. Twenty-five healthy cats were randomly divided into 5 groups: gastric-distention group (model group), tacrine group (cholinesterase inhibitor), tacrine + sham acupoint group (control group), tacrine + PC6 (neiguan) group, and tacrine + ST36 (zusanli) ...

متن کامل

Electroacupuncture at ST36 Protects ICC Networks via mSCF/Kit-ETV1 Signaling in the Stomach of Diabetic Mice

Background. Electroacupuncture (EA) at ST36 has been used to regulate gastric motility and effectively improve gastric emptying in diabetic patients. Nevertheless, the specific mechanisms underlying the efficacy of this treatment remain unknown. The aim of this study was to assess the variations of interstitial cells of Cajal (ICC) and explore the changes in mSCF/KIT-ETV1 signaling in the antru...

متن کامل

Therapeutic effect and mechanism of electroacupuncture at Zusanli on plasticity of interstitial cells of Cajal: a study of rat ileum

BACKGROUND Electroacupuncture (EA) is one of the techniques of acupuncture and is believed to be an effective alternative and complementary treatment in many disorders. The aims of this study were to investigate the effects and mechanisms of EA at acupoint Zusanli (ST36) on the plasticity of interstitial cells of Cajal (ICCs) in partial bowel obstruction. METHODS A Sprague Dawley rat model of...

متن کامل

Author's response to reviews Title:Electroacupuncture-like stimulation at Baihui and Dazhui acupoints exerts neuroprotective effects through activation of the brain-derived neurotrophic factor-mediated MEK1/2/ERK1/2/p90RSK/Bad signaling pathway in mild transient focal cerebral ischemia in rats Authors:

Title:Electroacupuncture-like stimulation at Baihui and Dazhui acupoints exerts neuroprotective effects through activation of the brain-derived neurotrophic factor-mediated MEK1/2/ERK1/2/p90RSK/Bad signaling pathway in mild transient focal cerebral ischemia in rats

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012